What is a side effect of taking ACE Inhibitors?

Angioedema is a well-known side effect associated with ACE inhibitors. ACE inhibitors work by blocking the enzyme that converts angiotensin I to angiotensin II, which causes blood vessels to constrict and raises blood pressure. While this mechanism is beneficial for treating hypertension and heart failure, it can also lead to an accumulation of bradykinin, a peptide that can cause swelling. Angioedema is characterized by significant swelling, often around the eyes and lips, and may also affect the throat, leading to difficulty in breathing. This side effect can be serious and may require immediate medical attention, highlighting the importance of monitoring patients on ACE inhibitors.

Other possible side effects related to ACE inhibitors include cough and hypotension, but angioedema stands out as a potentially life-threatening reaction that necessitates prompt medical intervention. Consequently, angioedema is recognized as a critical concern when prescribing ACE inhibitors, making it an important point for healthcare providers to monitor closely in patients receiving this class of medication.